Review



quinazoline qnz  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    MedChemExpress quinazoline qnz
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Quinazoline Qnz, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 54 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/quinazoline qnz/product/MedChemExpress
    Average 94 stars, based on 54 article reviews
    quinazoline qnz - by Bioz Stars, 2026-03
    94/100 stars

    Images

    1) Product Images from "Trophoblast cell surface antigen 2 (TROP2) from ascitic extracellular vesicles drives peritoneal metastasis of ovarian cancer by mesothelial-to-mesenchymal transition"

    Article Title: Trophoblast cell surface antigen 2 (TROP2) from ascitic extracellular vesicles drives peritoneal metastasis of ovarian cancer by mesothelial-to-mesenchymal transition

    Journal: Journal of Ovarian Research

    doi: 10.1186/s13048-025-01845-6

    QNZ inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Figure Legend Snippet: QNZ inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001

    Techniques Used: Blocking Assay, Western Blot, Migration



    Similar Products

    n 2 methoxyphenyl methyl n methyl  (Enamine Ltd)
    93
    Enamine Ltd n 2 methoxyphenyl methyl n methyl
    N 2 Methoxyphenyl Methyl N Methyl, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/n 2 methoxyphenyl methyl n methyl/product/Enamine Ltd
    Average 93 stars, based on 1 article reviews
    n 2 methoxyphenyl methyl n methyl - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    quinazoline qnz  (MedChemExpress)
    94
    MedChemExpress quinazoline qnz
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Quinazoline Qnz, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/quinazoline qnz/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    quinazoline qnz - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    quinazoline 183 qnz  (MedChemExpress)
    94
    MedChemExpress quinazoline 183 qnz
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Quinazoline 183 Qnz, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/quinazoline 183 qnz/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    quinazoline 183 qnz - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    tert butoxy quinazoline 2 4 diamine  (TargetMol)
    94
    TargetMol tert butoxy quinazoline 2 4 diamine
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Tert Butoxy Quinazoline 2 4 Diamine, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tert butoxy quinazoline 2 4 diamine/product/TargetMol
    Average 94 stars, based on 1 article reviews
    tert butoxy quinazoline 2 4 diamine - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    tetrahydropyrazolo 1 5 a quinazoline 3 carbonitrile 13 brown crystals  (Enamine Ltd)
    92
    Enamine Ltd tetrahydropyrazolo 1 5 a quinazoline 3 carbonitrile 13 brown crystals
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Tetrahydropyrazolo 1 5 A Quinazoline 3 Carbonitrile 13 Brown Crystals, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tetrahydropyrazolo 1 5 a quinazoline 3 carbonitrile 13 brown crystals/product/Enamine Ltd
    Average 92 stars, based on 1 article reviews
    tetrahydropyrazolo 1 5 a quinazoline 3 carbonitrile 13 brown crystals - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier
    morpholinyl quinazoline s  (Enamine Ltd)
    92
    Enamine Ltd morpholinyl quinazoline s
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Morpholinyl Quinazoline S, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/morpholinyl quinazoline s/product/Enamine Ltd
    Average 92 stars, based on 1 article reviews
    morpholinyl quinazoline s - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier
    quinazoline (qnz  (Millipore)
    90
    Millipore quinazoline (qnz
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Quinazoline (Qnz, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/quinazoline (qnz/product/Millipore
    Average 90 stars, based on 1 article reviews
    quinazoline (qnz - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    quinazoline scaffolds  (Enamine Ltd)
    92
    Enamine Ltd quinazoline scaffolds
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    Quinazoline Scaffolds, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/quinazoline scaffolds/product/Enamine Ltd
    Average 92 stars, based on 1 article reviews
    quinazoline scaffolds - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier
    6-amino-4-(4-phenoxyphenylethylamino) quinazoline qnz  (Shanghai Yuanye Biotechnology)
    90
    Shanghai Yuanye Biotechnology 6-amino-4-(4-phenoxyphenylethylamino) quinazoline qnz
    <t>QNZ</t> inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001
    6 Amino 4 (4 Phenoxyphenylethylamino) Quinazoline Qnz, supplied by Shanghai Yuanye Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/6-amino-4-(4-phenoxyphenylethylamino) quinazoline qnz/product/Shanghai Yuanye Biotechnology
    Average 90 stars, based on 1 article reviews
    6-amino-4-(4-phenoxyphenylethylamino) quinazoline qnz - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    QNZ inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001

    Journal: Journal of Ovarian Research

    Article Title: Trophoblast cell surface antigen 2 (TROP2) from ascitic extracellular vesicles drives peritoneal metastasis of ovarian cancer by mesothelial-to-mesenchymal transition

    doi: 10.1186/s13048-025-01845-6

    Figure Lengend Snippet: QNZ inhibits the MMT process by blocking the TNF-α/NF-κB pathway. A - H . Western blot analysis showed that TROP2-overexpressing EVs significantly altered the protein levels of E-cadherin, N-cadherin, vimentin, p-NF-κB p65, TNF-α, and TROP2 in HMrSV5 cells, which were reversed by QNZ (100 nM) treatment. I - J . Effects of TROP2-overexpressing EVs on migration in HMrSV5 cells with or without QNZ (100 nM) treatment. K - M . Effects of TROP2-overexpressing EVs on adhesion of ovarian cancer cells to HMrSV5 cells with or without QNZ (100 nM) treatment. Data are representative of at least three independent experiments and are presented as mean ± SD. ** P < 0.01, *** P < 0.001

    Article Snippet: D-Luciferin potassium salt was obtained from Yeasen (China), recombinant human TGF-β1 and human IL-1β were from R&D Systems (USA), and quinazoline (QNZ) was purchased from MCE (USA).

    Techniques: Blocking Assay, Western Blot, Migration